They thrashed Burnley 3-0 in Premier League opener on Friday. Ruben Dias, Bernardo Silva and Kevin De Bruyne are sidelined. John Stones and Kyle Walker are available.
Manchester City dominated from the off away at Burnley, where they grabbed a comfortable win.
Erling Haaland kicked off the new season in style, as he netted a brace to help Man City secure the victory.
Starting centre-back Dias is out injured, but Stones and right-back Walker are available for selection and could start on Wednesday.
Man City star De Bruyne is sidelined after suffering an injury against Burnley. A solid Mateo Kovacic could start, but De Bruyne is a key player for City.
Starting attacking midfielder Silva is sidelined due to illness. Phil Foden could fill in, with Jack Grealish starting on the left.